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U.S. overdose deaths decreased for over two years, marking the longest decline in decades, with a 27% drop in 2024.
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Approximately 73,000 overdose deaths were reported in the year ending August 2025, a 21% decrease from the previous year.
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Decreases in overdose deaths occurred in 45 states, with exceptions including Arizona, Hawaii, Kansas, New Mexico, and North Dakota.
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Potential factors for the decline include increased naloxone availability, expanded addiction treatment, and regulatory changes in China.
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Research suggests that pandemic stimulus payments may have initially contributed to overdose trends, with economic relief impacting drug use.