Neurodevelopmental outcomes at 3–12 months corrected age in predominantly enteral-fed very low birth weight infants in a resource-limited South African setting - Takeaways - MDSpire

Neurodevelopmental outcomes at 3–12 months corrected age in predominantly enteral-fed very low birth weight infants in a resource-limited South African setting

  • By

  • Muneerah Satardien

  • J. I. Van Zyl

  • Lizelle van Wyk

  • Evette Van Niekerk

  • Mirjam M Van Weissenbruch

  • July 1, 2026

  • 0 min

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  • 1

    The study assessed neurodevelopmental outcomes in very low birth weight infants (VLBWIs) in a resource-limited South African setting.

  • 2

    Of 296 VLBWIs, 190 (64.2%) attended the 12-month assessment, with a mean HINE score of 75.2, indicating mostly normal neurodevelopment.

  • 3

    Extrauterine growth restriction (EUGR) was prevalent at 33.7%, but it was not associated with neurodevelopmental impairment at 12 months.

  • 4

    Late-onset sepsis and metabolic bone disease were linked to increased odds of abnormal neurodevelopmental outcomes.

  • 5

    The study highlights the need for longer-term follow-up to evaluate potential later-emerging neurodevelopmental impairments.

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