Analysis of clinicopathological features and prognosis of mesenteric versus anti-mesenteric rectal cancer: a single-center retrospective cohort study - Takeaways - MDSpire

Analysis of clinicopathological features and prognosis of mesenteric versus anti-mesenteric rectal cancer: a single-center retrospective cohort study

  • By

  • Dalei Hao

  • Longzhan Dong

  • Xiangpeng Xi

  • Yulin Liu

  • Yongbo Zhang

  • Kang Xu

  • Jingbo Chen

  • July 10, 2026

  • 0 min

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  • 1

    The study analyzed 380 rectal cancer patients to compare outcomes based on tumor location: mesenteric versus anti-mesenteric.

  • 2

    The anti-mesenteric group showed a significantly lower 3-year local recurrence-free survival rate compared to the mesenteric group.

  • 3

    No significant differences in 3-year disease-free survival or overall survival were found between the two tumor location groups.

  • 4

    Age, surgical procedure, pathological T stage, and pathological N stage were identified as independent prognostic factors for overall survival.

  • 5

    Preoperative MRI assessment of axial tumor location provides valuable information for local recurrence risk and surgical planning.

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