Cognitive function and depressive symptoms in major depressive disorder: a smartphone-based study of outpatients from a sleep-disorders clinic in China - Takeaways - MDSpire

Cognitive function and depressive symptoms in major depressive disorder: a smartphone-based study of outpatients from a sleep-disorders clinic in China

  • By

  • Ci Yan

  • Pan Yan

  • Zhenghe Yu

  • Junhang Zhang

  • Mingfen Song

  • Hongjing Mao

  • April 16, 2026

  • 0 min

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  • 1

    Subjective cognitive dysfunction is prevalent in major depressive disorder (MDD) and correlates with depressive symptom severity.

  • 2

    Higher baseline scores on the Perceived Deficits Questionnaire for Depression (PDQ-D-20) predict poorer antidepressant response.

  • 3

    The study utilized data from the Good Sleep 365 smartphone platform to assess cognitive and depressive symptoms in MDD patients.

  • 4

    Results indicated that cognitive impairment is a core dimension of MDD, impacting treatment outcomes and daily functioning.

  • 5

    Routine cognitive assessments may help identify MDD patients at risk for suboptimal treatment outcomes in clinical settings.

Original Source(s)

Cognitive function and depressive symptoms in major depressive disorder: a smartphone-based study of outpatients from a sleep-disorders clinic in China

  • by Ci Yan, Pan Yan, Zhenghe Yu, Junhang Zhang, Mingfen Song, Hongjing Mao

  • April 16, 2026

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