Peer Referral Pathways and 6-Month Outcomes in a Tirzepatide-Supported Digital Weight Loss Service: Retrospective Cohort Study - Takeaways - MDSpire
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Evaluation of Peer Referral Strategies and Outcomes at 6 Months in a Digital Weight Loss Program Utilizing Tirzepatide: A Retrospective Cohort Analysis

  • By

  • Louis Talay

  • Laura Swinckels

  • Jason Hom

  • Marilyn Tan

  • Neera Ahuja

  • September 28, 2026

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  • 1

    The study evaluated the impact of peer referral on adherence and weight loss in a digital weight loss program using tirzepatide.

  • 2

    A total of 2576 referred patients and 31,873 nonreferred patients were included in the analysis.

  • 3

    Medication adherence at 6 months was significantly higher in referred patients (48%) compared to nonreferred patients (42%).

  • 4

    Per-protocol persistence was also greater in referred patients (35%) than in nonreferred patients (27%).

  • 5

    Mean weight loss at 6 months was 16.2% for referred patients and 14.1% for nonreferred patients, showing a significant difference.

Original Source(s)

Peer Referral Pathways and 6-Month Outcomes in a Tirzepatide-Supported Digital Weight Loss Service: Retrospective Cohort Study

  • by Louis Talay, Laura Swinckels, Jason Hom, Marilyn Tan, Neera Ahuja

  • September 28, 2026

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