Case Report and retrospective literature analysis of pediatric lower esophageal squamous cell carcinoma: focus on diagnostic challenges and therapeutic strategies - Takeaways - MDSpire

Case Report and retrospective literature analysis of pediatric lower esophageal squamous cell carcinoma: focus on diagnostic challenges and therapeutic strategies

  • By

  • Jiani Hu

  • Xianlan Xiang

  • Yichao Zhou

  • Peng Cai

  • Menglei Zhu

  • Jie Zhu

  • April 30, 2026

  • 0 min

Share

  • 1

    Pediatric lower esophageal squamous cell carcinoma is rare, with a case reported in a 10-year-old boy diagnosed at stage IIIA.

  • 2

    Symptoms of pediatric esophageal cancer are non-specific, often leading to misdiagnosis and delayed treatment.

  • 3

    Current treatment protocols for pediatric esophageal squamous cell carcinoma are not standardized and primarily rely on adult studies.

  • 4

    The patient underwent chemotherapy and laparoscopic gastrostomy, but the disease progressed, resulting in death seven months post-diagnosis.

  • 5

    A comprehensive approach combining neoadjuvant chemoradiotherapy with surgery may improve survival outcomes in selected pediatric cases.

Original Source(s)

Case Report and retrospective literature analysis of pediatric lower esophageal squamous cell carcinoma: focus on diagnostic challenges and therapeutic strategies

  • by Jiani Hu, Xianlan Xiang, Yichao Zhou, Peng Cai, Menglei Zhu, Jie Zhu

  • April 30, 2026

Related Content

Percutaneous nephrostomy as a marker of clinical vulnerability in non-metastatic muscle-invasive bladder cancer: prognostic and infectious implications

Author Correction: The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2

Use of PCSK9 Inhibitors Among Patients Receiving Immune Checkpoint Inhibitors for Cancer