Characterization of Unique Symptom Patterns in Patients with Primary Brain Tumors: A Prospective Longitudinal Analysis - Takeaways - MDSpire

Characterization of Unique Symptom Patterns in Patients with Primary Brain Tumors: A Prospective Longitudinal Analysis

  • By

  • Rongqing Li

  • Zikai Zhang

  • Xin Zhang

  • Jiefang Song

  • Yawen Wu

  • Linzhi Wu

  • Sailu Mao

  • Jinxia Jiang

  • Li Zeng

  • December 26, 2025

  • 0 min

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  • 1

    Brain tumors exhibit diverse symptoms, including headaches, seizures, and cognitive impairments, with significant variability based on tumor characteristics.

  • 2

    Surgery is the primary treatment for brain tumors, effectively removing tissue and alleviating symptoms, but diagnosis and management remain challenging.

  • 3

    This study employs Latent Profile Analysis to identify distinct symptom patterns in primary brain tumor patients at three perioperative time points.

  • 4

    Participants included adults with primary brain tumors undergoing surgery, with symptom data collected on admission, three days post-surgery, and two weeks post-surgery.

  • 5

    The MD Anderson Symptom Inventory Brain Tumor Module was utilized to assess symptom severity, providing insights into the unique challenges faced by these patients.

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