Etiology, diagnosis, and management of chronic pancreatitis associated primary complications: a narrative review - Takeaways - MDSpire

Etiology, diagnosis, and management of chronic pancreatitis associated primary complications: a narrative review

  • By

  • Liqi Sun

  • Mengruo Jiang

  • Xiaoyun Wang

  • Yuwei Sun

  • Yatao Tu

  • Zhaoshen Li

  • Lisi Peng

  • Haojie Huang

  • July 9, 2026

  • 0 min

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  • 1

    Chronic pancreatitis is characterized by irreversible fibrosis, leading to structural damage and functional decline of the pancreas.

  • 2

    Common complications of chronic pancreatitis include pancreatic exocrine and endocrine insufficiency, pain, and pancreatic duct stones.

  • 3

    The prevalence of pancreatic exocrine insufficiency increases significantly with disease duration, reaching about 70% by 20 years.

  • 4

    Diagnosis of pancreatic exocrine insufficiency can be performed using indirect tests like fecal human elastase-1 for its simplicity and cost-effectiveness.

  • 5

    This review aims to provide a comprehensive reference for the etiology, diagnosis, and management of complications associated with chronic pancreatitis.

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