Dry Eye Across Autoimmune Diseases

The nationwide analysis found the highest rates of dry eye disease among patients with Sjögren’s syndrome.

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Dry eye disease (DED) often precedes autoimmune disease diagnosis by approximately 3 years and varies in prevalence across different conditions.
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Sjögren’s syndrome and rheumatoid arthritis were the most common autoimmune diseases in the study, with DED affecting 81% and 39% of patients, respectively.
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DED prevalence ranged from 23% in Crohn’s disease to 81% in Sjögren’s syndrome, with females more commonly affected than males.
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Keratitis and corneal ulcers were significant ocular complications, particularly in patients with Sjögren’s syndrome and vasculitis.
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The study emphasizes the need for early recognition and management of DED to mitigate ocular morbidity in autoimmune disease populations.

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