Dry eye disease (DED) often precedes autoimmune disease diagnosis by approximately 3 years and varies in prevalence across different conditions.
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Sjögren’s syndrome and rheumatoid arthritis were the most common autoimmune diseases in the study, with DED affecting 81% and 39% of patients, respectively.
3
DED prevalence ranged from 23% in Crohn’s disease to 81% in Sjögren’s syndrome, with females more commonly affected than males.
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Keratitis and corneal ulcers were significant ocular complications, particularly in patients with Sjögren’s syndrome and vasculitis.
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The study emphasizes the need for early recognition and management of DED to mitigate ocular morbidity in autoimmune disease populations.
The approval was based on reduced proteinuria, and an ongoing trial is required to determine whether atacicept slows long-term kidney function decline.
