Mediastinal mass as a rare manifestation of paragonimiasis in a pediatric patient: a case study and examination of diagnostic difficulties - Takeaways - MDSpire

Mediastinal mass as a rare manifestation of paragonimiasis in a pediatric patient: a case study and examination of diagnostic difficulties

  • By

  • Shuchun Yang

  • Li Song

  • Qingwei Guo

  • February 16, 2026

  • 0 min

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  • 1

    Paragonimiasis is a zoonotic disease caused by Paragonimus trematodes, affecting approximately 23 million people globally, mainly in Asia.

  • 2

    A 13-year-old girl presented with a mediastinal mass, initially misdiagnosed as pneumonia, highlighting diagnostic challenges in paragonimiasis.

  • 3

    Imaging revealed a mixed-density mass in the right anterior superior mediastinum, with significant enhancement post-contrast.

  • 4

    Histopathological examination confirmed parasitic cysts, leading to a diagnosis of paragonimiasis after the patient’s dietary history was reviewed.

  • 5

    The patient responded well to praziquantel treatment, demonstrating the importance of individualized therapy based on clinical and imaging findings.

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