Familial Co-Aggregation of Neurodevelopmental Conditions and Childhood-Onset Type 1 Diabetes - Takeaways - MDSpire
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Co-Occurrence of Neurodevelopmental Disorders and Early-Onset Type 1 Diabetes in Families

  • By

  • Shengxin Liu

  • Gisele Magarotto Machado

  • Irzam Hardiansyah

  • Xinyue Gu

  • Jonas F. Ludvigsson

  • Paul Lichtenstein

  • Soffia Gudbjörnsdottir

  • Ebba Du Rietz

  • Brian D'Onofrio

  • Henrik Larsson

  • Mark J. Taylor

  • Ralf Kuja-Halkola

  • Agnieszka Butwicka

  • August 22, 2026

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  • 1

    Type 1 diabetes (T1D) is a prevalent chronic disorder that often begins in childhood and is associated with neurodevelopmental conditions (NDCs).

  • 2

    Neurodevelopmental conditions include ADHD, autism, and intellectual disability, affecting approximately 235 million individuals worldwide.

  • 3

    The study investigates the familial co-occurrence of childhood-onset T1D and NDCs, focusing on shared genetic and environmental factors.

  • 4

    Data for the study was sourced from several Swedish national registers, including the National Patient Register and the Total Population Register.

  • 5

    The cohort comprised over 4 million individuals born in Sweden, with analyses examining the relationship between T1D and NDCs among relatives.

Original Source(s)

Familial Co-Aggregation of Neurodevelopmental Conditions and Childhood-Onset Type 1 Diabetes

  • by Shengxin Liu, Gisele Magarotto Machado, Irzam Hardiansyah, Xinyue Gu, Jonas F. Ludvigsson, Paul Lichtenstein, Soffia Gudbjörnsdottir, Ebba Du Rietz, Brian D'Onofrio, Henrik Larsson, Mark J. Taylor, Ralf Kuja-Halkola, Agnieszka Butwicka

  • August 22, 2026

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