Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation for Patients with Decompensated Liver Cirrhosis - Takeaways - MDSpire

Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation for Patients with Decompensated Liver Cirrhosis

  • By

  • Zepeng Li

  • Xiaoling Zhou

  • Lu Han

  • Meijie Shi

  • Huanming Xiao

  • Ming Lin

  • Xiaoling Chi

  • January 26, 2023

  • 0 min

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  • 1

    Cirrhosis is a leading cause of morbidity and mortality, with limited treatment options, especially in the decompensated stage.

  • 2

    Human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs) offer a less invasive alternative for treating liver cirrhosis.

  • 3

    Prior studies indicate that HUCB-MSCs can improve liver function, but long-term efficacy and safety data are lacking.

  • 4

    This study evaluated the long-term outcomes of HUCB-MSC transplantation in patients with decompensated liver cirrhosis.

  • 5

    A total of 201 patients were enrolled, with 36 receiving HUCB-MSCT and 165 in a non-transplant group, matched for baseline characteristics.

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