The impact of the SARS-CoV-2 pandemic on umbilical cord blood transplantation in Japan: insights from an interrupted time series analysis

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The COVID-19 pandemic significantly impacted healthcare, particularly affecting hematopoietic stem cell transplantation (HSCT) activities globally.
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In Japan, HSCT activities remained stable during the pandemic, contrasting with declines reported in other regions.
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Umbilical cord blood transplantation (CBT) is the primary donor source in Japan, providing a safe alternative during emergencies like the pandemic.
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The study utilized interrupted time series analysis to assess the impact of COVID-19 on CBT choices in Japan from 2011 to 2021.
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Data from the TRUMP 2 registry indicated a total of 40,444 allogeneic HSCT cases were analyzed, with a focus on trends before and after the pandemic.

Bone Marrow Transplantation

by Nobuhiko Nakamura, Tetsuji Morishita, Hiromi Hayashi, Motohito Okabe, Hideki Nakasone, Naoyuki Uchida, Noriko Doki, Takahiro Fukuda, Satoshi Yoshihara, Masatsugu Tanaka, Tetsuya Nishida, Yuta Hasegawa, Ken-ichi Matsuoka, Masashi Sawa, Tetsuya Eto, Makoto Onizuka, Yuta Katayama, Koji Kato, Fumihiko Ishimaru, Ken Tabuchi, Yoshiko Atsuta, Nobuhiro Kanemura, Takanori Teshima
April 17, 2025

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