The CT-based attenuation index of peri-bowel adipose tissue can predict disease progression in inflammatory bowel disease patients - Takeaways - MDSpire

The CT-based attenuation index of peri-bowel adipose tissue can predict disease progression in inflammatory bowel disease patients

  • By

  • Jun Lu

  • Hui Xu

  • Jingxuan Zhang

  • Tianxin Cheng

  • Jing Zheng

  • Xinjun Han

  • Yuxin Wang

  • Xuxu Meng

  • Xiaoyang Li

  • Jiahui Jiang

  • Xue Dong

  • Zhenchang Wang

  • Zhenghan Yang

  • Lixue Xu

  • October 22, 2025

  • 0 min

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  • 1

    Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn’s disease, characterized by chronic immune-mediated inflammation.

  • 2

    The peri-bowel fat attenuation index (FAI) can quantify peri-bowel fat inflammation, potentially predicting disease progression in IBD patients.

  • 3

    Current noninvasive risk factors for IBD progression include CRP, ESR, and fecal calprotectin, but they are not ultimate targets in treatment strategies.

  • 4

    CT enterography and magnetic resonance enterography are routine imaging tools for assessing disease activity and complications in IBD.

  • 5

    The study aims to identify high-risk IBD patients using peri-bowel FAI to improve early intervention and long-term outcomes.

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