Toward a Rational Use of Probiotics in Very Preterm Infants - Takeaways - MDSpire

Optimizing Probiotic Administration for Very Preterm Infants

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1

Necrotizing enterocolitis (NEC) causes approximately 1 infant death daily in the US, highlighting the need for effective prevention strategies.
2

Probiotic use in US NICUs was discontinued in 2023, leading to a 60% increase in NEC incidence.
3

In Sweden, probiotic use among very preterm infants rose to 65% after national recommendations, significantly reducing NEC and mortality.
4

Probiotic supplementation was associated with a 75% reduction in overall NEC and an 84% reduction in mortality among infants receiving it.
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Concerns about probiotic-associated infections exist, but no cases were reported in Swedish NICUs during the study period.