Letter to the Editor: Retrospective Modeling Study of ChatGPT (GPT-4) Warfarin Dose Adjustment in Patients with INRs Outside the Therapeutic Range - Takeaways - MDSpire

Letter to the Editor: Retrospective Modeling Study of ChatGPT (GPT-4) Warfarin Dose Adjustment in Patients with INRs Outside the Therapeutic Range

  • By

  • Mehmet U. Çalışkan

  • Gökhan Keskin

  • May 27, 2026

  • 0 min

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  • 1

    The study highlights the potential role of ChatGPT in INR monitoring and warfarin dose adjustment in cardiology.

  • 2

    The INR target range was uniformly set at 2.0–3.0, which may not reflect patient-specific clinical needs.

  • 3

    Warfarin dosing in practice is constrained by fixed tablet strengths, complicating the application of calculated doses.

  • 4

    Discrepancies between clinician-derived and LLM-generated dosing recommendations may lead to misleading interpretations.

  • 5

    Future research should focus on AI-supported clinical decision support systems for more effective anticoagulant management.

Original Source(s)

Letter to the Editor: Retrospective Modeling Study of ChatGPT (GPT-4) Warfarin Dose Adjustment in Patients with INRs Outside the Therapeutic Range

  • by Mehmet U. Çalışkan, Gökhan Keskin

  • May 27, 2026

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