Assessment of Glucose Disposal Rate Changes and the Onset of Cardiovascular Disease in Patients with Stages 0–3 of Cardiovascular–Kidney–Metabolic Syndrome: A Prospective Cohort Analysis from China - Takeaways - MDSpire

Assessment of Glucose Disposal Rate Changes and the Onset of Cardiovascular Disease in Patients with Stages 0–3 of Cardiovascular–Kidney–Metabolic Syndrome: A Prospective Cohort Analysis from China

  • By

  • Jia Liu

  • Wendong Xu

  • Yue Zhang

  • Yuan Jia

  • Shiru Bai

  • Lu Er

  • Rongpin Du

  • November 26, 2025

  • 0 min

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  • 1

    Cardiovascular–kidney–metabolic syndrome (CKM) significantly increases the risk of adverse health events, affecting 90% of adults globally.

  • 2

    The estimated glucose disposal rate (eGDR) is a promising surrogate marker for insulin resistance, outperforming traditional methods in predicting cardiovascular risk.

  • 3

    This study utilized data from the CHARLS to explore the relationship between eGDR changes and new-onset cardiovascular disease in CKM patients.

  • 4

    Longitudinal evaluation of eGDR is crucial for precise risk stratification and management of cardiovascular disease in CKM syndrome.

  • 5

    The CHARLS study included 2,862 participants after applying strict inclusion criteria, ensuring a representative sample for the analysis.

Original Source(s)

Assessment of Glucose Disposal Rate Changes and the Onset of Cardiovascular Disease in Patients with Stages 0–3 of Cardiovascular–Kidney–Metabolic Syndrome: A Prospective Cohort Analysis from China

  • by Jia Liu, Wendong Xu, Yue Zhang, Yuan Jia, Shiru Bai, Lu Er, Rongpin Du

  • November 26, 2025

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