Worldwide Rates and Determinants of Depression and Anxiety Among Individuals with Liver Cirrhosis: A Systematic Review and Meta-Analysis - Takeaways - MDSpire

Worldwide Rates and Determinants of Depression and Anxiety Among Individuals with Liver Cirrhosis: A Systematic Review and Meta-Analysis

  • By

  • Omar Abureesh

  • Araek Al-Shraideh

  • Joelle Sleiman

  • Chloe Lahoud

  • Brendan Plann-Curley

  • Liliane Deeb

  • April 17, 2026

  • 0 min

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  • 1

    Liver cirrhosis affects approximately 122 million patients globally and is associated with significant psychological burdens.

  • 2

    The pooled prevalence of depression among cirrhotic patients is 37%, while anxiety prevalence is 53%, indicating a high mental health impact.

  • 3

    Age, alcoholism, and viral etiologies are significant risk factors linked to increased depression incidence in patients with cirrhosis.

  • 4

    Depression and anxiety in cirrhosis patients substantially impair quality of life and reduce treatment adherence.

  • 5

    Standardizing screening for depression and anxiety in cirrhosis patients could significantly improve their health outcomes.

Original Source(s)

Worldwide Rates and Determinants of Depression and Anxiety Among Individuals with Liver Cirrhosis: A Systematic Review and Meta-Analysis

  • by Omar Abureesh, Araek Al-Shraideh, Joelle Sleiman, Chloe Lahoud, Brendan Plann-Curley, Liliane Deeb

  • April 17, 2026

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