One patient with synchronous multiple primary colon cancers which is easy to miss: a case report - Takeaways - MDSpire
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A Case Report of Synchronous Multiple Primary Colon Cancers: A Rare Presentation Often Overlooked

  • By

  • Xinmin Bao

  • Haoru Liu

  • Ming Wu

  • Xianwei Liu

  • September 15, 2026

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  • 1

    Multiple primary colon cancer (MPCC) is an uncommon form of colon cancer, categorized as synchronous or metachronous.

  • 2

    A 70-year-old woman presented with sigmoid colon cancer and endoscopic obstruction, leading to a complex surgical intervention.

  • 3

    Enhanced abdominal CT revealed bowel-wall thickening and intussusception, along with two lesions in the transverse colon.

  • 4

    Intraoperative findings confirmed multiple synchronous adenocarcinomas in the sigmoid, transverse, and ascending colon.

  • 5

    Postoperative pathology confirmed the presence of moderately differentiated adenocarcinomas with varying degrees of invasion.

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