Quantification of PET activation in adipose tissue from non-contrast CT scans - Takeaways - MDSpire

Quantification of PET activation in adipose tissue from non-contrast CT scans

  • By

  • Carlos Cano-Espinosa

  • Michael W. Subrize

  • Elisa Franquet

  • Aaron M. Cypess

  • Gerald Kolodny

  • George R. Washko

  • Raúl San José Estépar

  • February 5, 2026

  • 0 min

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  • 1

    Brown adipose tissue (BAT) is crucial for energy metabolism and cardiometabolic health.

  • 2

    A deep learning model was developed to estimate metabolic activity in adipose tissue using non-contrast CT imaging.

  • 3

    The model was trained on paired PET/CT data from two independent cohorts, demonstrating strong predictive accuracy.

  • 4

    This method provides a radiation-sparing alternative for assessing adipose metabolic activity in clinical settings.

  • 5

    The approach could facilitate population-based studies of BAT and metabolic health using routine chest CT scans.

Original Source(s)

Quantification of PET activation in adipose tissue from non-contrast CT scans

  • by Carlos Cano-Espinosa, Michael W. Subrize, Elisa Franquet, Aaron M. Cypess, Gerald Kolodny, George R. Washko, Raúl San José Estépar

  • February 5, 2026

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