Impact of Chlorella vulgaris Supplementation on Health Outcomes in Individuals with Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis Evaluated by GRADE - Takeaways - MDSpire

Impact of Chlorella vulgaris Supplementation on Health Outcomes in Individuals with Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis Evaluated by GRADE

  • By

  • Ali Jafari

  • Helia Mardani

  • Bahare Parsi Nezhad

  • Azita Hekmatdoost

  • February 7, 2026

  • 0 min

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  • 1

    Non-alcoholic fatty liver disease (NAFLD) affects over 5% of hepatocytes and can progress to severe liver disorders.

  • 2

    Chlorella vulgaris supplementation may improve liver function and metabolic parameters in individuals with NAFLD.

  • 3

    This systematic review and meta-analysis is the first to evaluate C. vulgaris effects on cardiovascular risk factors in NAFLD patients.

  • 4

    The study utilized the GRADE framework to assess the quality of evidence regarding C. vulgaris supplementation.

  • 5

    Further research is needed to confirm the long-term benefits and mechanisms of C. vulgaris in supporting cardiovascular health.

Original Source(s)

Impact of Chlorella vulgaris Supplementation on Health Outcomes in Individuals with Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis Evaluated by GRADE

  • by Ali Jafari, Helia Mardani, Bahare Parsi Nezhad, Azita Hekmatdoost

  • February 7, 2026

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