Impact of Preoperative Suspension of Antiplatelet Therapy on Thrombotic Events Following Minimally Invasive Surgery for Abdominopelvic Cancer in Patients Using P2Y12 Inhibitors - Takeaways - MDSpire

Impact of Preoperative Suspension of Antiplatelet Therapy on Thrombotic Events Following Minimally Invasive Surgery for Abdominopelvic Cancer in Patients Using P2Y12 Inhibitors

  • By

  • Masashi Kubota

  • Satomi Yoshida

  • Takayuki Goto

  • Toshiki Fukasawa

  • Takayuki Anno

  • Gaku Fujiwara

  • Satoshi Toshiyama

  • Yoshihide Inayama

  • Takanori Yanai

  • Takayuki Sumiyoshi

  • Ryoichi Saito

  • Takashi Kobayashi

  • Koji Kawakami

  • January 16, 2026

  • 0 min

Share

  • 1

    Minimally invasive surgery (MIS) is increasingly used for treating abdominopelvic cancers due to its superior bleeding control.

  • 2

    P2Y12 inhibitors effectively prevent arterial thrombotic disease but increase the risk of hemorrhagic complications during surgery.

  • 3

    Current guidelines recommend a preoperative discontinuation of 5 days for clopidogrel and 7 days for prasugrel before high-bleeding-risk surgeries.

  • 4

    This study analyzes the impact of preoperative suspension versus maintenance of P2Y12 inhibitors on thrombotic events in MIS for cancer.

  • 5

    Data were collected from large Japanese hospital databases, focusing on patients undergoing radical surgery while on P2Y12 inhibitors.

Original Source(s)

Impact of Preoperative Suspension of Antiplatelet Therapy on Thrombotic Events Following Minimally Invasive Surgery for Abdominopelvic Cancer in Patients Using P2Y12 Inhibitors

  • by Masashi Kubota, Satomi Yoshida, Takayuki Goto, Toshiki Fukasawa, Takayuki Anno, Gaku Fujiwara, Satoshi Toshiyama, Yoshihide Inayama, Takanori Yanai, Takayuki Sumiyoshi, Ryoichi Saito, Takashi Kobayashi, Koji Kawakami

  • January 16, 2026

Related Content

Financial Hardship and Nonadherence to Lifestyle and Surveillance in Childhood Cancer Survivors

An explainable streaming early identification model for early neurological deterioration based on coordinated fusion of ECG waveforms and vital signs

Cognitive outcomes after endovascular thrombectomy in ischemic stroke: a systematic review