The optimal exercise for improving inhibitory control in children and adolescents with NDDs: a systematic review and network meta-analysis - Takeaways - MDSpire

The optimal exercise for improving inhibitory control in children and adolescents with NDDs: a systematic review and network meta-analysis

  • By

  • Tianyang Zhang

  • Fanzhi Zeng

  • Feng Li

  • Bowen Niu

  • May 20, 2026

  • 0 min

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  • 1

    Inhibitory control deficits are common in children and adolescents with neurodevelopmental disorders (NDDs) and are linked to neurophysiological abnormalities.

  • 2

    This study utilized a network meta-analysis of 45 randomized controlled trials to evaluate exercise effects on inhibitory control in NDDs.

  • 3

    Aerobic and mind-body exercises significantly improved inhibitory control compared to conventional control groups, with mind-body exercise showing the highest effectiveness.

  • 4

    Mind-body exercise received the highest SUCRA ranking (87.1), suggesting it may be the optimal intervention for enhancing inhibitory control in affected children.

  • 5

    The findings indicate that non-pharmacological interventions like exercise therapy could be beneficial alternatives to pharmacological treatments for NDDs.

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