Cardiometabolic Index: a novel prognostic biomarker for recurrent stroke risk in acute ischemic stroke patients - Takeaways - MDSpire

Cardiometabolic Index: a novel prognostic biomarker for recurrent stroke risk in acute ischemic stroke patients

  • By

  • Yue Wang

  • Yingying Ding

  • Min Han

  • Yehong Liu

  • Tao Xin

  • June 10, 2026

  • 0 min

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  • 1

    Stroke is a significant global health issue, with recurrent stroke being a serious complication for patients with acute ischemic stroke (AIS).

  • 2

    The study involved 588 AIS patients who received thrombolytic therapy, assessing the Cardiometabolic Index (CMI) as a prognostic biomarker.

  • 3

    CMI showed superior predictive performance for long-term adverse cerebrovascular events compared to traditional biomarkers in post-thrombolytic AIS patients.

  • 4

    A high CMI value (≥0.80) was independently associated with an increased risk of major adverse cerebrovascular events (MACEs).

  • 5

    Systemic inflammation partially mediated the predictive effect of CMI on adverse clinical outcomes in AIS patients after thrombolytic therapy.

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