The relationship between cardiac and liver iron evaluated by MR imaging in haematological malignancies and chronic liver disease

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Cardiac iron accumulation is a significant cause of mortality in thalassemia major and has been linked to adverse outcomes in myelodysplastic syndrome.
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MRI is a reliable, non-invasive method for quantifying iron concentration in the liver and myocardium, offering better sensitivity and specificity than serum ferritin.
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The study aimed to explore the relationship between cardiac and liver iron accumulation in non-chelated patients with myelodysplastic syndrome and chronic liver disease.
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In patients with myelodysplastic syndrome, cardiac iron excess may occur primarily in those with severe liver iron overload, as suggested by preliminary studies.
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The study included 87 subjects, with MRI imaging conducted to assess iron levels, highlighting the need for accurate iron measurement in clinical practice.

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