Risk factor analysis and prediction model construction for delayed erythroid hematopoietic reconstitution after allogeneic hematopoietic stem cell transplantation: a single-center retrospective study - Takeaways - MDSpire

Risk factor analysis and prediction model construction for delayed erythroid hematopoietic reconstitution after allogeneic hematopoietic stem cell transplantation: a single-center retrospective study

  • By

  • Qianqian Zhang

  • Fangfang Ge

  • Lijie Han

  • Mengmeng Yan

  • Rong Guo

  • Zhongxing Jiang

  • July 13, 2026

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  • 1

    The study identified independent risk factors for delayed erythroid hematopoietic recovery after allogeneic hematopoietic stem cell transplantation.

  • 2

    Key risk factors include pre-transplant ferritin levels, severity of anemia, and donor-recipient ABO blood type compatibility.

  • 3

    The predictive model demonstrated an area under the curve (AUC) of 0.835, indicating good discrimination for predicting delayed recovery.

  • 4

    The study involved 165 patients categorized into delayed and non-delayed erythroid hematopoietic reconstitution groups.

  • 5

    The findings aim to facilitate early identification of high-risk individuals for targeted interventions post-transplant.

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