Impact of cannabis use and tobacco smoking on outcomes of open carpal tunnel release surgery: a nationwide study in the United States - Takeaways - MDSpire

Impact of cannabis use and tobacco smoking on outcomes of open carpal tunnel release surgery: a nationwide study in the United States

  • By

  • Amir Human Hoveidaei

  • Sina Esmaeili

  • Ruby Gilmor

  • Zhongming Chen

  • Janet D. Conway

  • John V. Ingari

  • June 23, 2026

  • 0 min

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  • 1

    Carpal tunnel syndrome affects 4-5% of the global population and can lead to significant functional impairments.

  • 2

    Cannabis use in the U.S. increased by 120% from 2008 to 2022, while tobacco use among young adults decreased significantly.

  • 3

    Cannabis and tobacco use are associated with increased perioperative risks and complications after orthopedic surgeries.

  • 4

    The study analyzed data from over 1.2 million patients who underwent open carpal tunnel release surgery from 2010 to 2022.

  • 5

    Postoperative complications, including surgical site infections, varied significantly among patients based on substance use.

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