Complete revascularization and heart failure risk in acute coronary syndrome across the ejection fraction spectrum: focus on LVEF-dependent effects - Takeaways - MDSpire

Complete revascularization and heart failure risk in acute coronary syndrome across the ejection fraction spectrum: focus on LVEF-dependent effects

  • By

  • Xiaozhi Luo

  • Jiaan Nong

  • Shaowei Xu

  • Zhongyuan Meng

  • Xingshou Pan

  • May 18, 2026

  • 0 min

Share

  • 1

    Complete revascularization (CR) significantly reduces the risk of heart failure hospitalization or cardiovascular death in patients with LVEF 40%-50%.

  • 2

    In the study, 4.6% of patients in the CR group reached the primary endpoint compared to 7.8% in the incomplete revascularization (ICR) group.

  • 3

    The benefit of CR was most pronounced in patients with non-ST-segment elevation ACS (NSTE–ACS) and LVEF <50%.

  • 4

    As LVEF increased, the efficacy of CR in reducing heart failure risk diminished, indicating a potential LVEF-dependent effect.

  • 5

    The observational nature of the study suggests caution in interpreting the results, highlighting the need for further research.

Original Source(s)

Complete revascularization and heart failure risk in acute coronary syndrome across the ejection fraction spectrum: focus on LVEF-dependent effects

  • by Xiaozhi Luo, Jiaan Nong, Shaowei Xu, Zhongyuan Meng, Xingshou Pan

  • May 18, 2026

Related Content

Analysis of factors associated with cognitive impairment in elderly patients hospitalized with chronic heart failure

Predictive value of the uric acid-to-albumin ratio for contrast-induced nephropathy after percutaneous coronary intervention and construction of a clinical prediction model in patients with coronary artery disease

Beyond recovery: long-term cardiovascular risks after severe COVID-19 requiring intensive care