Effects of accelerated intermittent θ burst stimulation on depressive episodes and cognitive function in adolescents with bipolar disorder - Takeaways - MDSpire
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Impact of Enhanced Intermittent Theta Burst Stimulation on Depressive Symptoms and Cognitive Abilities in Adolescents with Bipolar Disorder

  • By

  • Yingshuang Xue

  • Hong Wang

  • Jihui Yue

  • Shenglin Wen

  • December 22, 2025

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  • 1

    Bipolar disorder in adolescents is prevalent and often presents with depressive episodes, leading to significant disability and treatment challenges.

  • 2

    Current treatments for adolescent bipolar depression lack FDA-approved medications, necessitating the exploration of alternative therapeutic strategies.

  • 3

    Accelerated intermittent theta burst stimulation (aiTBS) shows promise in reducing depressive symptoms and improving cognitive abilities in adolescents.

  • 4

    Research on the efficacy and safety of aiTBS in adolescents with bipolar depression is limited, highlighting the need for further studies.

  • 5

    The study aims to evaluate the therapeutic and cognitive effects of aiTBS in adolescents diagnosed with bipolar depression.

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