Acceptance and commitment therapy for prevention of chronic pain after total knee arthroplasty - Takeaways - MDSpire

Acceptance and commitment therapy for prevention of chronic pain after total knee arthroplasty

  • By

  • Emanuele Maria Giusti

  • Gianluca Castelnuovo

  • Chiara Manna

  • Giorgia Varallo

  • Roberto Cattivelli

  • Benito Vanni Petrachi

  • Marco Stramba-Badiale

  • Chiara A M Spatola

  • October 23, 2025

  • 0 min

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  • 1

    The NOPAIN treatment, based on acceptance and commitment therapy, aims to prevent chronic postsurgical pain after total knee arthroplasty.

  • 2

    Eighty patients participated in the study, with a high retention rate of 81.3% completing all treatment sessions.

  • 3

    Significant improvements were observed in pain intensity, knee pain, stiffness, and function after 3 months of the NOPAIN treatment.

  • 4

    Female sex and age were linked to lower odds of moderate-to-severe pain, while central sensitization and psychological factors increased pain risk.

  • 5

    The study suggests that integrating ACT-based treatments like NOPAIN into rehabilitation may help mitigate chronic pain following TKA.

Original Source(s)

Acceptance and commitment therapy for prevention of chronic pain after total knee arthroplasty

  • by Emanuele Maria Giusti, Gianluca Castelnuovo, Chiara Manna, Giorgia Varallo, Roberto Cattivelli, Benito Vanni Petrachi, Marco Stramba-Badiale, Chiara A M Spatola

  • October 23, 2025

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