Glycemic variability and muscle loss in elderly type 2 diabetes: insights from continuous glucose monitoring and chest CT in 303 patients - Takeaways - MDSpire

Glycemic variability and muscle loss in elderly type 2 diabetes: insights from continuous glucose monitoring and chest CT in 303 patients

  • By

  • Xiao-le Zhang

  • Ning Bai

  • Chun-pu Mao

  • Chun-yan Liu

  • June 22, 2026

  • 0 min

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  • 1

    The study involved 303 elderly patients with type 2 diabetes mellitus who underwent continuous glucose monitoring and chest CT.

  • 2

    Glycemic variability indicators such as CV, SD, MAGE, and TBR were independently associated with lower pectoralis muscle mass.

  • 3

    CV explained the largest proportion of variance in pectoralis muscle index, followed by TBR, SD, and MAGE.

  • 4

    The inverse association between glycemic variability and muscle mass was stronger in patients with longer diabetes duration and lower BMI.

  • 5

    The findings suggest that stabilizing glucose fluctuations may be important for preserving muscle mass in older adults with diabetes.

Original Source(s)

Glycemic variability and muscle loss in elderly type 2 diabetes: insights from continuous glucose monitoring and chest CT in 303 patients

  • by Xiao-le Zhang, Ning Bai, Chun-pu Mao, Chun-yan Liu

  • June 22, 2026

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