Influencing factors of cognitive frailty in older patients with esophageal cancer undergoing chemotherapy: a mixed-methods study - Takeaways - MDSpire

Influencing factors of cognitive frailty in older patients with esophageal cancer undergoing chemotherapy: a mixed-methods study

  • By

  • Fan Wang

  • Zhie Gu

  • Yixin Jia

  • Yuhui Li

  • Quan Mao

  • Yusheng Shu

  • June 16, 2026

  • 0 min

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  • 1

    The study examined cognitive frailty prevalence and factors among older esophageal cancer patients undergoing chemotherapy.

  • 2

    Cognitive frailty incidence was found to be 45.1% in the studied population of older patients.

  • 3

    Significant factors associated with cognitive frailty included chemotherapy cycles, nutritional risk, and sleep disturbances.

  • 4

    The study utilized a mixed-methods design, combining quantitative data with qualitative interviews for comprehensive analysis.

  • 5

    Findings aim to support early identification of cognitive frailty and inform targeted nursing interventions in clinical practice.

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