Current status and influencing factors of laryngopharyngeal reflux disease in outpatients with laryngeal diseases: key considerations for clinical practice - Takeaways - MDSpire

Current status and influencing factors of laryngopharyngeal reflux disease in outpatients with laryngeal diseases: key considerations for clinical practice

  • By

  • Longfang Zhang

  • Yingchuan Wu

  • Yuanyuan Yang

  • May 18, 2026

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  • 1

    Laryngopharyngeal reflux disease (LPRD) is a prevalent comorbidity in outpatients with laryngeal disorders, significantly impacting quality of life.

  • 2

    Independent risk factors for LPRD include age ≥65, BMI ≥25 kg/m2, smoking, strong tea preference, abnormal LES function, laryngeal surgery history, and hypertension.

  • 3

    A prediction model based on seven risk factors was developed, achieving a sensitivity of 0.723 and specificity of 0.892 for diagnosing LPRD.

  • 4

    Abnormal LES function was identified as the most significant risk factor for LPRD, with the highest odds ratio of 2.376.

  • 5

    The study emphasizes the need for early identification and intervention in LPRD to improve treatment outcomes and reduce complications.

Original Source(s)

Current status and influencing factors of laryngopharyngeal reflux disease in outpatients with laryngeal diseases: key considerations for clinical practice

  • by Longfang Zhang, Yingchuan Wu, Yuanyuan Yang

  • May 18, 2026

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