Seasonal variation in Ménière disease: a systematic review and meta-analysis - Takeaways - MDSpire

Seasonal variation in Ménière disease: a systematic review and meta-analysis

  • By

  • Xuanyu Shi

  • Linlin Wang

  • Xingqian Shen

  • Ziying Xu

  • Yangming Leng

  • Bo Liu

  • July 2, 2026

  • 0 min

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  • 1

    This meta-analysis investigates the association between seasonal patterns and the occurrence of Ménière disease (MD).

  • 2

    Five observational studies involving 1,001,636 participants were included, assessing seasonal occurrence of MD as the primary outcome.

  • 3

    The odds ratios for MD occurrence were 1.03 in spring, 0.92 in winter, and 1.04 in autumn, with summer as the reference.

  • 4

    Subgroup and sensitivity analyses confirmed the robustness of the findings, indicating no single study drove the overall estimate.

  • 5

    The study highlights the need for further high-quality research across diverse geographic regions to solidify evidence on seasonal variation in MD.

Original Source(s)

Seasonal variation in Ménière disease: a systematic review and meta-analysis

  • by Xuanyu Shi, Linlin Wang, Xingqian Shen, Ziying Xu, Yangming Leng, Bo Liu

  • July 2, 2026

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