Case Report: Torque teno virus identified in pleural effusion of pediatric severe Mycoplasma pneumoniae pneumonia: diagnostic and therapeutic implications - Takeaways - MDSpire

Case Report: Torque teno virus identified in pleural effusion of pediatric severe Mycoplasma pneumoniae pneumonia: diagnostic and therapeutic implications

  • By

  • Jiaxin Liang

  • Hanwei Ma

  • Yuanxiao Li

  • Xingxing Dai

  • Xingchuan Li

  • June 2, 2026

  • 0 min

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  • 1

    Mycoplasma pneumoniae pneumonia can lead to massive pleural effusion in 1%-20% of pediatric cases, requiring careful clinical management.

  • 2

    Targeted next-generation sequencing identified macrolide-resistant Mycoplasma pneumoniae and Torque teno virus in pleural effusion of two children.

  • 3

    Both pediatric patients recovered after closed thoracic drainage and adjusted anti-mycoplasma therapy based on resistance findings.

  • 4

    Torque teno virus detection in pleural fluid remains uncertain in clinical significance and may indicate immune perturbation rather than pathogenicity.

  • 5

    Broader pathogen testing in pleural fluid could enhance diagnostic evaluation in complex infections, warranting further controlled studies.

Original Source(s)

Case Report: Torque teno virus identified in pleural effusion of pediatric severe Mycoplasma pneumoniae pneumonia: diagnostic and therapeutic implications

  • by Jiaxin Liang, Hanwei Ma, Yuanxiao Li, Xingxing Dai, Xingchuan Li

  • June 2, 2026

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