I-FABP, Citrulline, and Non-Invasive Indicators of Liver Dysfunction in Depressed Patients: Findings from a Cross-Sectional Study - Takeaways - MDSpire

I-FABP, Citrulline, and Non-Invasive Indicators of Liver Dysfunction in Depressed Patients: Findings from a Cross-Sectional Study

  • By

  • Jakub Rogalski

  • Joanna Grzelczyk

  • Aleksandra Margulska

  • Grzegorz Mirocha

  • Grażyna Budryn

  • Dominik Strzelecki

  • Oliwia Gawlik-Kotelnicka

  • January 3, 2026

  • 0 min

Share

  • 1

    The study investigates the relationship between liver dysfunction and gut biomarkers in patients with depression and metabolic syndrome.

  • 2

    Citrulline and I-FABP are highlighted as potential biomarkers for assessing intestinal dysfunction and liver abnormalities.

  • 3

    Non-invasive hepatic indices like FSI, HSI, APRI, and FIB-4 are relevant for early detection of liver issues without invasive procedures.

  • 4

    The study population consists of 116 subjects diagnosed with depressive disorders, recruited for a trial on probiotic supplementation.

  • 5

    The research aims to explore how dietary, behavioral, and psychosocial factors influence liver and gut health in depressed patients.

Original Source(s)

I-FABP, Citrulline, and Non-Invasive Indicators of Liver Dysfunction in Depressed Patients: Findings from a Cross-Sectional Study

  • by Jakub Rogalski, Joanna Grzelczyk, Aleksandra Margulska, Grzegorz Mirocha, Grażyna Budryn, Dominik Strzelecki, Oliwia Gawlik-Kotelnicka

  • January 3, 2026

Related Content

TyG-WHtR predicts incident type 2 diabetes mellitus in NAFLD: a 12-year prospective cohort study

Worldwide Rates and Determinants of Depression and Anxiety Among Individuals with Liver Cirrhosis: A Systematic Review and Meta-Analysis

Covert hepatic encephalopathy as a multi-organ syndrome: the gut–liver–muscle–brain axis, diagnosis, treatment, and multidisciplinary care