Sex Steroids and Women’s Physical Performance in Midlife: Findings From the Menarche-To-PreMenopause Study - Takeaways - MDSpire
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The Impact of Sex Hormones on Physical Performance in Midlife Women: Insights from the Menarche-to-PreMenopause Research

  • By

  • Leticia W Ribeiro

  • Jenny Doust

  • Gregore I Mielke

  • Jenny A Visser

  • Gita D Mishra

  • September 26, 2025

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  • 1

    The study examined the impact of sex hormones on physical performance in middle-aged Australian women aged 44.6 years.

  • 2

    Estrogen levels, particularly estrone, were negatively associated with chair rise performance in the participants.

  • 3

    Higher concentrations of dihydrotestosterone (DHT) and sex hormone-binding globulin (SHBG) were linked to improved standing balance.

  • 4

    The research highlights the importance of sex steroids in physical performance, particularly during the menopausal transition.

  • 5

    Findings suggest that age and body size may also influence the relationship between sex hormones and physical function.

Original Source(s)

Sex Steroids and Women’s Physical Performance in Midlife: Findings From the Menarche-To-PreMenopause Study

  • by Leticia W Ribeiro, Jenny Doust, Gregore I Mielke, Jenny A Visser, Gita D Mishra

  • September 26, 2025

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