Genomic Epidemiology and Evolution of Rhinovirus in Western Washington State, 2021–2022 - Takeaways - MDSpire

Genomic Epidemiology and Evolution of Rhinovirus in Western Washington State, 2021–2022

  • By

  • Stephanie Goya

  • Seffir T Wendm

  • Hong Xie

  • Tien V Nguyen

  • Sarina Barnes

  • Rohit R Shankar

  • Jaydee Sereewit

  • Kurtis Cruz

  • Ailyn C Pérez-Osorio

  • Margaret G Mills

  • Alexander L Greninger

  • July 4, 2024

  • 0 min

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  • 1

    Human rhinoviruses (RVs) are a major cause of the common cold and can lead to severe respiratory issues in immunocompromised individuals.

  • 2

    The study sequenced 1078 RV genomes to analyze viral evolution during two distinct periods affected by the COVID-19 pandemic in Washington State.

  • 3

    99 of 168 known RV genotypes were detected, with evidence of intergenotypic recombination and genotype cluster swapping between 2021 and 2022.

  • 4

    A significant association was found between symptom presence and viral load, but not with specific RV species or genotypes.

  • 5

    The findings highlight the dynamic nature of RV genomic epidemiology and the need for further investigation into RV genotype and serotype correlations.

Original Source(s)

Genomic Epidemiology and Evolution of Rhinovirus in Western Washington State, 2021–2022

  • by Stephanie Goya, Seffir T Wendm, Hong Xie, Tien V Nguyen, Sarina Barnes, Rohit R Shankar, Jaydee Sereewit, Kurtis Cruz, Ailyn C Pérez-Osorio, Margaret G Mills, Alexander L Greninger

  • July 4, 2024

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