Effects of long-term inhaled corticosteroids on growth velocity and adult height in children with asthma: a systematic review and meta-analysis - Takeaways - MDSpire
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Impact of Prolonged Inhaled Corticosteroid Use on Growth Rate and Final Height in Pediatric Asthma: A Systematic Review and Meta-Analysis

  • By

  • Jinguang Zhao

  • Aiai Dong

  • Yibu Kong

  • Tianlong Xie

  • Xinyan Yu

  • Baoxin Li

  • Tianbao Tan

  • Jiqiang Mi

  • Yinan Guo

  • September 14, 2026

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  • 1

    This systematic review and meta-analysis evaluated the impact of prolonged inhaled corticosteroid use on growth in children with asthma.

  • 2

    Thirteen studies met the inclusion criteria, with six providing data for quantitative analysis on linear growth velocity.

  • 3

    The primary analysis showed no significant reduction in linear growth velocity with ICS treatment, but sensitivity analysis indicated a potential small decrease.

  • 4

    Among school-age children, a reduction in growth velocity was observed, while evidence on adult height was limited and suggested a small decrease.

  • 5

    The findings warrant cautious interpretation, considering the established benefits of inhaled corticosteroids in asthma management.

Original Source(s)

Effects of long-term inhaled corticosteroids on growth velocity and adult height in children with asthma: a systematic review and meta-analysis

  • by Jinguang Zhao, Aiai Dong, Yibu Kong, Tianlong Xie, Xinyan Yu, Baoxin Li, Tianbao Tan, Jiqiang Mi, Yinan Guo

  • September 14, 2026

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