Regional intra-arterial infusion chemotherapy combined with deep hyperthermia and targeted therapy followed by radiotherapy for recurrence with intestinal obstruction after radical resection of rectal cancer in an elderly patient: a case report of individualized treatment - Takeaways - MDSpire

Regional intra-arterial infusion chemotherapy combined with deep hyperthermia and targeted therapy followed by radiotherapy for recurrence with intestinal obstruction after radical resection of rectal cancer in an elderly patient: a case report of individualized treatment

  • By

  • Guangsheng Zhao

  • Shunhang Yin

  • Xinyu Zhou

  • Fang Xu

  • Licai Xu

  • Qiushi Wang

  • Jun Zhou

  • Lei Zhang

  • Song Liu

  • May 25, 2026

  • 0 min

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  • 1

    Local recurrence rates of rectal cancer can reach 20%-35% in elderly patients who do not receive adjuvant therapy.

  • 2

    An 81-year-old male developed local recurrence with complete intestinal obstruction four months after radical resection of rectal cancer.

  • 3

    A comprehensive treatment strategy included regional intra-arterial chemotherapy, deep hyperthermia, and sequential radiotherapy.

  • 4

    The patient achieved complete remission and long-term stable disease without severe adverse events during treatment.

  • 5

    Genetic testing revealed specific mutations and indicated sensitivity to certain chemotherapy and targeted therapy agents.

Original Source(s)

Regional intra-arterial infusion chemotherapy combined with deep hyperthermia and targeted therapy followed by radiotherapy for recurrence with intestinal obstruction after radical resection of rectal cancer in an elderly patient: a case report of individualized treatment

  • by Guangsheng Zhao, Shunhang Yin, Xinyu Zhou, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Lei Zhang, Song Liu

  • May 25, 2026

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