Long COVID Persistence and Surveillance Gaps Across 58 US Hospitals - Takeaways - MDSpire

Long COVID Persistence and Surveillance Gaps Across 58 US Hospitals

  • By

  • Jiazi Tian

  • Alaleh Azhir

  • Matthew Decaro

  • Ngan Chau

  • Jonas Hügel

  • Michele Morris

  • Jingya Cheng

  • Pedram Fard

  • Ingrid V. Bassett

  • Douglas S. Bell

  • Elmer V. Bernstam

  • Shyam Visweswaran

  • Jeffrey G. Klann

  • Shawn N. Murphy

  • Hossein Estiri

  • May 27, 2026

  • 0 min

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  • 1

    Postacute sequelae of SARS-CoV-2 infection (PASC) prevalence is estimated at 43%, contrasting with lower figures from diagnostic coding.

  • 2

    Patients with PASC show increased healthcare utilization, including higher hospitalization rates and specialist consultations.

  • 3

    Longitudinal studies indicate that 45% of COVID-19 survivors have unresolved symptoms at 4 months, with 30% persistent at 24 months.

  • 4

    The P2RC algorithm, an AI system, achieved 80% precision in identifying PASC cases, highlighting distinct endotypes based on organ involvement.

  • 5

    The study utilized EHR data from 58 hospitals across diverse US regions to quantify true PASC prevalence and assess chronic disease patterns.

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