Association of Systemic Inflammatory Markers with 28-Day Mortality in Patients with Severe Pneumonia: A Retrospective Study from a Single Center - Takeaways - MDSpire

Association of Systemic Inflammatory Markers with 28-Day Mortality in Patients with Severe Pneumonia: A Retrospective Study from a Single Center

  • By

  • Xingxing Chen

  • Weiqiang Huang

  • Wenjing Dai

  • Wei Zhang

  • Xiaofeng Zhong

  • Ming Hu

  • April 21, 2026

  • 0 min

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  • 1

    This study evaluated systemic inflammatory indices' association with 28-day mortality in 100 ICU patients with severe pneumonia.

  • 2

    SIRI and NLR were independently associated with 28-day mortality, while SII and IBI showed attenuated associations after adjustment.

  • 3

    Each 1-standard deviation increase in SIRI and NLR correlated with higher odds of 28-day death, indicating their prognostic value.

  • 4

    The study highlights the potential of inflammation-based indices for early risk stratification in severe pneumonia patients.

  • 5

    Findings suggest that SIRI and NLR may provide additional prognostic information beyond conventional severity markers.

Original Source(s)

Association of Systemic Inflammatory Markers with 28-Day Mortality in Patients with Severe Pneumonia: A Retrospective Study from a Single Center

  • by Xingxing Chen, Weiqiang Huang, Wenjing Dai, Wei Zhang, Xiaofeng Zhong, Ming Hu

  • April 21, 2026

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