Targeted Approaches for Addressing Taxane-Induced Neuropathic Pain in Breast Cancer Survivors: An In-Depth Review - Takeaways - MDSpire

Targeted Approaches for Addressing Taxane-Induced Neuropathic Pain in Breast Cancer Survivors: An In-Depth Review

  • By

  • Weydyson de Lima do Nascimento Anastácio

  • Tony Meireles dos Santos

  • Fabrício Oliveira Souto

  • Edmund O. Acevedo

  • April 13, 2026

  • 0 min

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  • 1

    Taxane-induced neuropathic pain (TINP) significantly impacts breast cancer survivors, affecting their quality of life and treatment adherence.

  • 2

    The review identifies key mechanisms of TINP, including mitochondrial dysfunction, oxidative stress, and neuroimmune activation.

  • 3

    Various interventions for TINP are explored, including pharmacological treatments, neuromodulation, physical activity, and manual therapies.

  • 4

    Current clinical trials show promise for TINP management but face limitations like small sample sizes and methodological inconsistencies.

  • 5

    There is a critical need for more rigorous studies focusing on mechanism-oriented interventions to improve TINP rehabilitation strategies.

Original Source(s)

Targeted Approaches for Addressing Taxane-Induced Neuropathic Pain in Breast Cancer Survivors: An In-Depth Review

  • by Weydyson de Lima do Nascimento Anastácio, Tony Meireles dos Santos, Fabrício Oliveira Souto, Edmund O. Acevedo

  • April 13, 2026

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