Plasma microRNA signatures in drug-Naïve Romanian adolescents with First-Episode Psychosis - Takeaways - MDSpire

Plasma microRNA signatures in drug-Naïve Romanian adolescents with First-Episode Psychosis

  • By

  • Grosu, Ștefania-Alexandra

  • Milanesi, Elena

  • Dobre, Maria

  • Pelisenco, Iulia Andreea

  • Paun, Radu-Mihai

  • Hinescu, Mihail Eugen

  • May 13, 2026

  • 0 min

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  • 1

    This study identifies the plasma microRNA profile in drug-naïve Romanian adolescents experiencing first-episode psychosis.

  • 2

    A total of 14 adolescents, including 7 with first-episode psychosis and 7 healthy controls, were assessed for miRNA levels.

  • 3

    Twenty-one miRNAs showed significant level differences between first-episode psychosis patients and healthy controls.

  • 4

    Certain miRNAs negatively correlated with symptom severity, while others showed positive correlations with symptom scores.

  • 5

    The findings suggest that circulating miRNAs could serve as potential early-stage biomarkers for psychotic disorders.

Original Source(s)

Plasma microRNA signatures in drug-Naïve Romanian adolescents with First-Episode Psychosis

  • by Grosu, Ștefania-Alexandra , Milanesi, Elena , Dobre, Maria , Pelisenco, Iulia Andreea , Paun, Radu-Mihai , Hinescu, Mihail Eugen

  • May 13, 2026

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