Risk factors for refractory BPPV: subtype-dependent association of serum 25-hydroxyvitamin D - Takeaways - MDSpire

Risk factors for refractory BPPV: subtype-dependent association of serum 25-hydroxyvitamin D

  • By

  • Hye Ah Joo

  • Sun A. Han

  • Jin Kim

  • Il-Seok Park

  • Min Young Kwak

  • June 3, 2026

  • 0 min

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  • 1

    In a study of 171 patients with acute BPPV, 27.5% were classified as having refractory BPPV, requiring three or more CRP attempts.

  • 2

    BPPV subtype and prior vestibular neuritis were identified as the strongest predictors of treatment resistance in the study.

  • 3

    Lower serum 25-hydroxyvitamin D levels were independently associated with treatment refractoriness in BPPV.

  • 4

    The association between 25(OH)D levels and treatment resistance was significant only in typical BPPV cases.

  • 5

    The study suggests that serum 25(OH)D may serve as a prognostic marker for metabolic vulnerability in typical BPPV.

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