Heel hidradenocarcinoma regarded as a corn for 25 years with subsequent multiorgan metastasis: a case report and literature review - Takeaways - MDSpire
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Hidradenocarcinoma of the heel misdiagnosed as a corn for 25 years leading to multiorgan metastasis: a case study and review of existing literature

  • By

  • Lianbo Yang

  • Ziang Zheng

  • Haoran Chen

  • Xinyao Cui

  • Jiabin Lin

  • Yifan Wang

  • Haidong Liang

  • Jing Yi

  • August 14, 2026

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  • 1

    Hidradenocarcinoma is a rare malignant tumor often misdiagnosed due to nonspecific clinical features, particularly in heel lesions.

  • 2

    A 44-year-old woman had a heel lesion misidentified as a corn for 25 years, leading to delayed diagnosis and treatment.

  • 3

    Histopathological analysis confirmed hidradenocarcinoma after an excisional biopsy, with all surgical margins showing negativity.

  • 4

    The patient developed inguinal and later skeletal and intracranial metastases, highlighting the aggressive nature of the disease.

  • 5

    Timely pathological assessment is crucial for persistent acral lesions to avoid misdiagnosis and ensure appropriate treatment.

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