Editorial: Managing COVID-19 in heart and lung transplantation: clinical challenges and emerging solutions - Takeaways - MDSpire

Editorial: Managing COVID-19 in heart and lung transplantation: clinical challenges and emerging solutions

  • By

  • Chengliang Yang

  • Wenjun Mao

  • Ömer Senbaklavaci

  • April 17, 2026

  • 0 min

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  • 1

    COVID-19 poses significant challenges in heart and lung transplantation, affecting infection risk and long-term outcomes.

  • 2

    Transplant recipients are vulnerable due to chronic immunosuppression, high comorbidity, and impaired immune responses to vaccination.

  • 3

    Research indicates that sirolimus may increase the risk of severe COVID-19, necessitating individualized immunosuppression strategies.

  • 4

    Long COVID affects approximately 5% of solid organ transplant recipients, with unclear implications for graft failure and mortality.

  • 5

    Therapeutic management of COVID-19 in immunocompromised patients presents challenges due to potential drug-drug interactions.

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