Linking the Geriatric Nutritional Risk Index to Postoperative Delirium: A Meta-Analytic Review - Takeaways - MDSpire

Linking the Geriatric Nutritional Risk Index to Postoperative Delirium: A Meta-Analytic Review

  • By

  • Dandan Han

  • Yingsi Liang

  • Qian Chen

  • Xinyu Wang

  • Xiao Chen

  • April 23, 2026

  • 0 min

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  • 1

    Low Geriatric Nutritional Risk Index (GNRI) is significantly associated with an increased risk of postoperative delirium (POD) in surgical patients.

  • 2

    The meta-analysis included 12 cohort studies with a total of 12,332 surgical patients, demonstrating a pooled risk ratio of 1.62 for low GNRI and POD.

  • 3

    Subgroup analyses revealed a stronger association between low GNRI and POD in patients older than 74 years and those with GNRI cutoffs below 98.

  • 4

    The association between GNRI and POD was weaker in studies employing multivariate analyses compared to univariate analyses.

  • 5

    Preoperative nutritional assessment using GNRI may help identify surgical patients at higher risk for developing postoperative delirium.

Original Source(s)

Linking the Geriatric Nutritional Risk Index to Postoperative Delirium: A Meta-Analytic Review

  • by Dandan Han, Yingsi Liang, Qian Chen, Xinyu Wang, Xiao Chen

  • April 23, 2026

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