The levels of vascular endothelial cells and endothelium-dependent vasomotor cytokines in children with essential hypertension: a case-control study - Takeaways - MDSpire

The levels of vascular endothelial cells and endothelium-dependent vasomotor cytokines in children with essential hypertension: a case-control study

  • By

  • Jingjing Ma

  • Yaxi Cui

  • Yao Lin

  • Yanyan Liu

  • Yang Liu

  • Lin Shi

  • June 18, 2026

  • 0 min

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  • 1

    The study assessed circulating endothelial cells, progenitor cells, and vasomotor cytokines in children with essential hypertension.

  • 2

    Children with essential hypertension had significantly higher levels of circulating endothelial cells and lower levels of endothelial progenitor cells.

  • 3

    Endothelium-dependent vasomotor cytokines, including nitrite and 6-keto-prostaglandin F1a, were significantly lower in hypertensive children.

  • 4

    Conversely, levels of endothelin-1 and thromboxane B2 were significantly higher in the hypertensive group.

  • 5

    The findings suggest that endothelial dysfunction may contribute to the pathogenesis of pediatric essential hypertension.

Original Source(s)

The levels of vascular endothelial cells and endothelium-dependent vasomotor cytokines in children with essential hypertension: a case-control study

  • by Jingjing Ma, Yaxi Cui, Yao Lin, Yanyan Liu, Yang Liu, Lin Shi

  • June 18, 2026

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