Case Report: Granular cell tumor of the axillary tail mimicking node-positive breast carcinoma — two cases with imaging–pathology correlation - Takeaways - MDSpire

Case Report: Granular cell tumor of the axillary tail mimicking node-positive breast carcinoma — two cases with imaging–pathology correlation

  • By

  • Yuming Shao

  • Yang Xu

  • Shasha Song

  • Hao Lin

  • Jie Zhang

  • June 11, 2026

  • 0 min

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  • 1

    Granular cell tumor of the breast (GCTB) is a rare neoplasm that often mimics invasive breast carcinoma on imaging.

  • 2

    Preoperative core needle biopsy (CNB) is crucial for accurate diagnosis of suspicious axillary tail masses to avoid unnecessary surgeries.

  • 3

    Case 1 involved a 53-year-old woman whose imaging suggested invasive carcinoma, but pathology confirmed benign GCTB after surgery.

  • 4

    Case 2 involved a 38-year-old woman diagnosed with benign GCTB through ultrasound-guided vacuum-assisted biopsy.

  • 5

    Both patients remained disease-free at 12 and 36 months, highlighting the importance of accurate preoperative diagnosis.

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